Visceraal vetweefsel (VAT)
MetaboolVet dat rond de interne organen in de buikholte is opgeslagen.
Ook bekend als: buikvet, visceraal vet, orgaanvet, Organfett
VAT is metabool actief en produceert inflammatoire cytokines en hormonen die de insulinegevoeligheid en stofwisseling beïnvloeden. Overmatig VAT is sterk geassocieerd met het metabool syndroom, hart- en vaatziekten, diabetes type 2 en bepaalde vormen van kanker.
Waarom dit belangrijk is
VAT is metabolically active "toxic" fat, releasing inflammatory cytokines and hormones directly into organs. High VAT causes no specific symptoms while dramatically increasing disease risk. It drives insulin resistance (requiring more insulin for blood sugar control), promotes inflammation, raises blood pressure, and causes fatty liver disease. Long-term consequences include type 2 diabetes, heart disease, stroke, and certain cancers.
VAT responds preferentially to exercise. You can reduce dangerous organ fat before seeing weight or waist changes.
Hoe dit samenhangt met andere biomarkers
- Visceral adipose tissue (VAT) is the deep fat that wraps around organs in the belly — it is the most metabolically active fat depot. Elevated VAT correlates with insulin resistance (HOMA-Index), unhealthy lipid patterns (high Apolipoprotein B, low HDL Cholesterol), elevated hs-CRP, and elevated Liver fat fraction (%PDFF).
- The VAT to SAT Ratio captures metabolic risk more sensitively than VAT alone.
- VAT loss with weight reduction is disproportionately greater than total fat loss — this explains most of the metabolic improvement seen with even modest weight loss.
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