Alanine aminotransferase (ALAT)
Stomach and gut healthALT is an enzyme mostly found in your liver — elevated levels in blood usually signal that liver cells have been damaged or irritated.
ALAT (Alanine Aminotransferase): An enzyme primarily found in liver cells. When liver cells are damaged, ALAT leaks into the bloodstream, making it a sensitive indicator of liver injury from various causes.
Why this matters
ALAT (Alanine Aminotransferase) acts as an early warning system for liver health. Elevations can signal conditions such as fatty liver disease, viral hepatitis, or medication-related liver stress before symptoms appear. Tracking ALAT helps guide early action through lifestyle measures like reducing alcohol intake, maintaining a healthy weight, exercising regularly, and eating a balanced diet.
How this connects to other biomarkers
- ALAT (also called ALT) is more specific to the liver than Aspartat-Aminotransferase (ASAT); an ASAT / ALAT ratio < 1 typically points to viral hepatitis or non-alcoholic fatty liver disease (NAFLD/MASLD).
- Persistent ALAT elevation with elevated Liver fat fraction (%PDFF), abdominal obesity, and high HOMA-Index confirms metabolic-associated fatty liver disease.
- Use Fibrose-Score (FIB-4) alongside transaminases to estimate liver scarring.
Frequently asked questions
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