Alpha-linolenic acid (18:3, ALA)
MetabolismAlpha-linolenic acid is a plant-derived omega-3 fatty acid found in flaxseed, chia, and walnuts.
It serves as a metabolic precursor for longer-chain omega-3 fatty acids such as EPA and DHA.
Reference range
415
Low
Normal
High
mg/l
Source: lab benchmark
Reference ranges may vary between labs and assays. Always interpret results with your healthcare provider.
Why this matters
Adequate ALA intake supports anti-inflammatory balance and cardiovascular health. However, the conversion to EPA and DHA in the body is limited, so direct dietary sources of these long-chain omega-3s are still important.
How this connects to other biomarkers
- Alpha-Linolenic Acid (ALA) is the plant-based omega-3 precursor; conversion to Eicosapentaenoic Acid (20:5, EPA) and Docosahexaenoic Acid (22:6, DHA) is inefficient (typically < 10%) and depends on age, sex, and competing Linoleic Acid (18:2, LA) intake.
- Adequate ALA intake without rising EPA/DHA (low Omega-3 Index) suggests poor conversion — direct EPA/DHA supplementation may be needed.
Included in
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