Dihomo-gamma-linolenic acid (20:3, DGLA)
MetabolismDGLA is a key omega-6 fatty acid formed from GLA.
It produces anti-inflammatory prostaglandins and acts as a metabolic balance point between GLA and arachidonic acid.
Why this matters
Higher DGLA levels are linked to reduced inflammation and improved immune balance. It plays an important role in moderating the effects of arachidonic acid.
How this connects to other biomarkers
- DGLA is a precursor to anti-inflammatory PGE1 and is elevated by Gamma-Linolenic Acid (18:3, GLA) intake (e.g. evening primrose, borage).
- The AA / DGLA Ratio indicates whether DGLA is being further desaturated to pro-inflammatory Arachidonic Acid (20:4, AA) — high ratios warrant addressing diet and insulin resistance (high HOMA-Index).
Included in
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