Estimated glomerular filtration rate (eGFR)
Bladder and kidney healtheGFR (estimated Glomerular Filtration Rate): Calculated using the CKD-EPI formula based on creatinine level, age, sex, and ethnic background.
It estimates how much blood your kidneys filter per minute, with normal values typically above 90 ml/min/1.73m². Values below 60 ml/min/1.73m² indicate moderate kidney impairment, while values below 30 ml/min/1.73m² signifies severe impairment.
Reference range
Source: Ahead Health benchmark
Reference ranges may vary between labs and assays. Always interpret results with your healthcare provider. · LOINC code: 62238-1
Why this matters
eGFR reveals potential kidney health issues before serious symptoms appear. Normal values are typically above 90 ml/min/1.73m². Values below 60 ml/min/1.73m² indicate moderate kidney impairment, while values below 30 ml/min/1.73m² signifies severe impairment. Early warning signs may include fatigue, swelling, or changes in urination.
Monitoring eGFR helps track kidney function over time, supporting lifestyle measures such as blood pressure control, hydration, and avoiding kidney-damaging medications.
How this connects to other biomarkers
- eGFR estimates kidney function from Creatinine; in extremes of muscle mass (sarcopenia, bodybuilders, amputees) estimated Glomerular Filtration Rate (eGFR) - Cystatin C is more accurate.
- eGFR < 60 ml/min/1.73m² for > 3 months defines chronic kidney disease (CKD); stages: G3a (45–59), G3b (30–44), G4 (15–29), G5 (< 15) — each step represents a meaningful loss of filtering capacity.
- Falling eGFR with rising Phosphate, low Calcium, and falling Hemoglobin indicates CKD progression with secondary mineral-bone disorder and anemia of CKD (the kidney also makes the hormone that drives red-cell production).
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