Fasting insulin
MetabolismFasting insulin measures baseline insulin levels necessary to maintain normal blood sugar.
Why this matters
Elevated fasting insulin often develops years before blood sugar rises and signals insulin resistance. Monitoring allows early metabolic intervention to prevent diabetes and cardiometabolic disease.
How this connects to other biomarkers
- Elevated Fasting Insulin with normal Fasting Glucose is an early sign of insulin resistance — the pancreas is producing more insulin than usual to keep glucose in range.
- Use HOMA-Index to combine fasting insulin and glucose into an insulin-sensitivity score; the Triglyceride-Glucose (TyG) Index is a useful surrogate when insulin testing is not available.
- Very low Fasting Insulin with elevated glucose suggests the pancreas can no longer make enough insulin (type 1 diabetes, late-stage type 2 with β-cell exhaustion, or pancreatic disease).
Included in
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