Triglyceride-glucose (TyG) index
MetabolismThe TyG index combines fasting triglycerides and glucose to estimate insulin resistance.
Reference range
Source: Ahead Health benchmark
Reference ranges may vary between labs and assays. Always interpret results with your healthcare provider.
Why this matters
TyG index complements HOMA-IR by capturing insulin resistance through lipid-glucose interactions, sometimes detecting metabolic dysfunction that HOMA-IR might miss. It's particularly sensitive to hepatic insulin resistance and atherogenic dyslipidemia. When used together with HOMA-IR, these indices provide a comprehensive view of metabolic health; HOMA-IR reflects pancreatic insulin output and peripheral sensitivity, while TyG reveals lipid-related metabolic stress. This dual approach improves detection of early insulin resistance, cardiovascular risk, and fatty liver disease, enabling more personalized intervention strategies.
How this connects to other biomarkers
- TyG Index (a calculation using Triglycerides and Fasting Glucose) is a surrogate for insulin resistance that does not require an insulin measurement.
- Values > 8.5 generally indicate insulin resistance and correlate well with HOMA-Index and metabolic syndrome diagnosis.
- Useful in routine practice and large-population screening since it relies only on standard lipid and glucose tests.
Included in
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