MCV
BloedcelsysteemMean Corpuscular Volume meet de gemiddelde grootte van rode bloedcellen.
Het helpt bij het diagnosticeren van verschillende soorten bloedarmoede: verhoogd bij macrocytaire anemie, verlaagd bij microcytaire anemie en normaal bij normocytaire anemie.
Referentiewaarden
Bron: lab benchmark
Referentiewaarden kunnen per lab en testmethode verschillen. Bespreek je uitslag altijd met je arts. · LOINC-code: 30428-7
Waarom dit belangrijk is
MCV levels provide early insight into red blood cell health before obvious symptoms like fatigue or weakness occur. Low MCV often indicates iron deficiency or chronic disease, while high MCV may point to vitamin B12 or folate deficiency or liver issues. MCV is also useful for distinguishing different types of anemia, helping guide appropriate dietary or medical interventions. Maintaining a balanced diet with adequate iron, B12, and folate, and monitoring any underlying health conditions, helps support healthy red blood cells and effective oxygen delivery.
Hoe dit samenhangt met andere biomarkers
- Low MCV (small red blood cells, "microcytic") with low Ferritin and Transferrin Saturation confirms iron-deficiency anemia; with normal iron studies consider thalassemia trait (an inherited red-cell disorder — confirm with hemoglobin electrophoresis).
- High MCV (large red blood cells, "macrocytic") with low Vitamin B12 or Folic acid (Vitamin B9) indicates megaloblastic anemia; with normal vitamins consider alcohol use, underactive thyroid (high TSH), or red cells breaking down (hemolysis — high LDH-1 (LDH Isoenzyme 1), low haptoglobin).
- Elevated RDW-CV alongside abnormal MCV suggests evolving or mixed deficiencies.
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