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Brain and nerve healthDetected by MRI

White matter disease

Damage to the brain's white matter tracts that connect different brain regions. MRI detects these changes, which can indicate vascular disease, inflammation, or demyelination.

Early detection matters

Our comprehensive check-up screens for white matter disease and hundreds of other conditions.

Related biomarkers we test

Thalamus volume

Normalized thalamic volume relative to total intracranial volume, allowing for standardized assessment across individuals with different head sizes. This proportional measurement helps identify selective thalamic atrophy that might indicate specific neurological conditions including multiple sclerosis and certain dementias.

Hippocampus volume

The hippocampus is crucial for memory formation and spatial navigation. Atrophy of the hippocampus is a hallmark of Alzheimer's disease and can also occur in other forms of dementia. It is associated with memory loss and disorientation.

Gray matter volume

Represents the percentage or ratio of gray matter volume to total intracranial volume. This metric helps identify disproportionate gray matter loss that exceeds normal aging or is inconsistent with head size, potentially indicating neurodegenerative processes.

Cortical gray matter volume

Normalized cortical gray matter volume relative to total intracranial volume, allowing for standardized assessment of cortical tissue across individuals with different head sizes.

Caudate volume

Normalized volume of the caudate nucleus relative to total intracranial volume, allowing for meaningful comparisons between individuals with different head sizes. This proportional measurement helps identify caudate-specific changes that may indicate neurodegenerative disorders affecting executive function and movement control.

Brain volume

The ratio of total brain volume to total intracranial volume. This value typically decreases with age as brain atrophy progresses. Accelerated decline in this ratio beyond age-expected norms may suggest pathological brain volume loss.

Related conditions in Brain and nerve health