AA / DGLA ratio
Heart healthThis ratio reflects the conversion efficiency from DGLA to arachidonic acid and the balance between anti- and pro-inflammatory omega-6 metabolites.
Why this matters
A higher ratio suggests an inflammatory shift in omega-6 metabolism. Monitoring helps identify imbalances that may contribute to chronic inflammatory states.
How this connects to other biomarkers
- Elevated AA/DGLA Ratio reflects high delta-5-desaturase activity — it tilts the body toward production of pro-inflammatory eicosanoids and is associated with insulin resistance and metabolic syndrome.
- A high ratio combined with elevated HOMA-Index and HbA1c (NGSP) strengthens the link to metabolic dysfunction.
- The ratio falls with omega-3 supplementation and improves the AA / EPA Ratio in parallel.
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