Anemia with abnormally large, deeply colored red blood cells, most often from vitamin B12 or folate deficiency. Blood testing identifies the pattern to guide targeted treatment.
Our comprehensive check-up screens for hyperchromic macrocytic anemia and hundreds of other conditions.
Mean Corpuscular Volume measures the average size of red blood cells. It helps diagnose different types of anemia - elevated in macrocytic anemia, decreased in microcytic anemia, and normal in normocytic anemia.
Mean corpuscular hemoglobin concentration (MCHC)Mean Corpuscular Hemoglobin Concentration measures the average concentration of hemoglobin in a given volume of red blood cells. It helps distinguish between different types of anemia and assess cell hydration status.
Mean corpuscular hemoglobin (MCH)Mean Corpuscular Hemoglobin measures the average amount of hemoglobin per red blood cell. It helps evaluate the hemoglobin content of cells and is used alongside other RBC indices to classify anemias.
Vitamin B12Vitamin B12 is a water-soluble vitamin essential for the production of red blood cells, the synthesis of DNA, and the healthy functioning of the nervous system. It also supports brain function and energy metabolism. The body cannot make B12 on its own and relies on dietary sources such as meat, fish, eggs, and dairy. Excess B12 is stored in the liver, so deficiency can take time to develop but may lead to serious health issues if not addressed.
Folic acid (Vitamin B9)Folic acid, or folate in its natural form, is a water-soluble B vitamin that plays a key role in cell division, DNA synthesis, and red blood cell formation. It is especially important during periods of rapid growth, such as pregnancy and adolescence. Folate is found in leafy greens, legumes, citrus fruits, and fortified foods. The body cannot produce folate and depends on regular dietary intake.
