An inherited disorder of iron metabolism that makes the body absorb too much iron, damaging the liver, heart, and pancreas. Blood testing detects raised transferrin saturation and ferritin before organ injury occurs.
Our comprehensive check-up screens for hereditary excess iron absorption (hemochromatosis) and hundreds of other conditions.
Transferrin saturation is the percentage of transferrin that is bound with iron. It reflects how much of the transport protein is being used.
TransferrinTransferrin is a liver-produced protein that transports iron in the blood to various tissues. It binds and carries iron to where it's needed.
R2* relaxation (R2*)A magnetic resonance parameter sensitive to iron concentration in tissues. Elevated hepatic R2* values suggest increased iron deposition in the liver (hemochromatosis or hemosiderosis).
IronIron is an essential trace element involved in the production of hemoglobin and the transport of oxygen in the blood. In circulation, most iron is bound to the protein transferrin.
FerritinFerritin is a protein that stores iron and releases it when needed. Ferritin levels in the blood reflect the body's iron storage.
Aspartate aminotransferase (ASAT)An enzyme present in liver, heart, muscle, and other tissues. While less specific to the liver than ALAT, elevated levels often indicate liver damage when other liver markers are also abnormal.
