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DigestiveDetected by blood test

Liver fibrosis (non-cirrhotic)

Scarring of liver tissue that precedes cirrhosis and is often reversible if caught early. Blood testing flags fibrosis through markers such as the FIB-4 score.

Early detection matters

Our comprehensive check-up screens for liver fibrosis (non-cirrhotic) and hundreds of other conditions.

Related biomarkers we test

Visceral adipose tissue (VAT)

Fat stored around internal organs within the abdominal cavity. VAT is metabolically active and produces inflammatory cytokines and hormones that affect insulin sensitivity and metabolism. Excessive VAT is strongly linked to metabolic syndrome, cardiovascular disease, type 2 diabetes, and certain cancers.

ASAT / ALAT ratio

This ratio compares two liver enzymes to give insight into liver health.

FIB-4 index

FIB-4 combines age, platelet count, and liver enzymes to estimate the degree of liver fibrosis.

R2* relaxation (R2*)

A magnetic resonance parameter sensitive to iron concentration in tissues. Elevated hepatic R2* values suggest increased iron deposition in the liver (hemochromatosis or hemosiderosis).

Protein, total

Total protein measures all proteins in blood plasma, primarily albumin and globulins. It helps evaluate nutritional status, liver function, and immune system health.

Liver fat fraction (%PDFF)

Proton Density Fat Fraction measurement of the liver, quantifying hepatic fat content. Elevated values indicate hepatic steatosis (fatty liver), which may progress to more severe liver disease.

Gamma-glutamyl transferase (GGT)

GGT (Gamma-Glutamyl Transferase): An enzyme particularly sensitive to alcohol consumption and certain medications. Elevated GGT can indicate bile duct issues, fatty liver disease, or alcohol-related liver damage.

Bilirubin, total

A yellow pigment produced when the body breaks down red blood cells. The liver processes bilirubin for elimination. Elevated total bilirubin can indicate liver dysfunction, bile duct obstruction, or increased red blood cell destruction.

Aspartate aminotransferase (ASAT)

An enzyme present in liver, heart, muscle, and other tissues. While less specific to the liver than ALAT, elevated levels often indicate liver damage when other liver markers are also abnormal.

Alkaline phosphatase

Found in multiple tissues (liver, bones, kidneys, and bile ducts), this enzyme helps break down proteins and is essential for many bodily functions. In liver contexts, elevated ALP often suggests bile duct obstruction.

Albumin

The most abundant protein in blood plasma, produced by the liver. In kidney contexts, low levels in blood may indicate protein loss through damaged kidneys, while presence of albumin in urine (albuminuria) is an important marker of kidney damage.

Alanine aminotransferase (ALAT)

ALAT (Alanine Aminotransferase): An enzyme primarily found in liver cells. When liver cells are damaged, ALAT leaks into the bloodstream, making it a sensitive indicator of liver injury from various causes.

Albumin/globulin (A/G) ratio

A calculated value comparing albumin (the main transport protein made by the liver) to globulins (a diverse group including antibodies, clotting factors, and inflammatory proteins). Since albumin normally comprises about 60% of total protein and globulins 40%, this ratio reflects the balance between liver synthetic function, nutritional status, and immune/inflammatory activity.

Related conditions in Digestive