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MetabolicDetected by blood test

Diabetes mellitus

A metabolic disorder in which the body can no longer properly regulate blood sugar; it can develop over years without symptoms and, left untreated, may damage blood vessels, kidneys, nerves, and eyes. Blood testing with HbA1c and fasting glucose detects diabetes and its early stages so that timely intervention is possible.

Early detection matters

Our comprehensive check-up screens for diabetes mellitus and hundreds of other conditions.

Related biomarkers we test

HbA1c (NGSP)

HbA1c (NGSP) expresses glycated hemoglobin as a percentage, reflecting average blood sugar levels over the past 2–3 months. It is the same measurement as HbA1c (IFCC) but reported in the older NGSP/DCCT unit system (%). An HbA1c of 5.7–6.4% indicates prediabetes; 6.5% or above suggests diabetes.

Sodium

Sodium is the primary electrolyte in blood that regulates fluid balance, nerve impulse transmission, and muscle contraction. Imbalances can cause neurological symptoms, fluid retention, or dehydration.

Potassium

Potassium is a crucial electrolyte for heart, nerve, and muscle function. It maintains proper cell electrical potential and helps regulate blood pressure. Imbalances can cause dangerous heart rhythm disturbances.

Estimated glomerular filtration rate (eGFR)

eGFR (estimated Glomerular Filtration Rate): Calculated using the CKD-EPI formula based on creatinine level, age, sex, and ethnic background. It estimates how much blood your kidneys filter per minute, with normal values typically above 90 ml/min/1.73m². Values below 60 ml/min/1.73m² indicate moderate kidney impairment, while values below 30 ml/min/1.73m² signifies severe impairment.

Creatinine

Creatinine is a waste product from muscle metabolism that's filtered by the kidneys and excreted in urine. Serum levels remain relatively constant with normal kidney function, making it a reliable marker for kidney filtration capacity. Elevated levels suggest reduced kidney function.

Omega-6 / Omega-3 ratio

This ratio compares total omega-6 to total omega-3 fatty acids, reflecting the overall balance of inflammatory and anti-inflammatory lipid mediators.

Triglyceride-glucose (TyG) index

The TyG index combines fasting triglycerides and glucose to estimate insulin resistance.

Fasting insulin

Fasting insulin measures baseline insulin levels necessary to maintain normal blood sugar.

HOMA-index

The HOMA index estimates insulin resistance using fasting glucose and insulin values.

Visceral adipose tissue (VAT)

Fat stored around internal organs within the abdominal cavity. VAT is metabolically active and produces inflammatory cytokines and hormones that affect insulin sensitivity and metabolism. Excessive VAT is strongly linked to metabolic syndrome, cardiovascular disease, type 2 diabetes, and certain cancers.

Total abdominal fat

The sum of all adipose tissue in the abdominal region, including both visceral and subcutaneous compartments. This measurement provides an overall assessment of abdominal adiposity.

Total abdominal adipose tissue index (L/m2)

A normalized measure of all abdominal fat (both visceral and subcutaneous) adjusted for height. It's calculated by dividing total abdominal fat volume by the square of height, allowing for standardized comparison between individuals of different body sizes.

HbA1c (IFCC)

Glycated hemoglobin according to International Federation of Clinical Chemistry standards. It's an alternative measurement system for HbA1c that uses different units (mmol/mol) than NGSP (percentage).

Fasting glucose

Fasting blood glucose measures blood sugar levels after fasting for at least 8 hours. It's used to screen for and monitor diabetes, with elevated levels indicating impaired glucose metabolism.

Abdominal fat ratio

The proportion of abdominal fat relative to total body fat. This measurement helps assess fat distribution patterns, which can be more clinically relevant than total fat alone. Higher abdominal fat ratios are associated with increased metabolic and cardiovascular risks.

Liver fat fraction (%PDFF)

Proton Density Fat Fraction measurement of the liver, quantifying hepatic fat content. Elevated values indicate hepatic steatosis (fatty liver), which may progress to more severe liver disease.

Heart risk score (SCORE2)

SCORE2 estimates your 10-year risk of heart attack or stroke based on blood pressure, cholesterol, age, and other factors.

Total cholesterol / HDL cholesterol ratio

This ratio evaluates overall cholesterol relative to protective HDL cholesterol. It is a commonly used measure of lipid-related cardiovascular risk.

Triglycerides

Triglycerides are the main form of fat stored in the body and circulating in blood. They serve as an energy source and are derived from calories not immediately used. Elevated levels increase risk of cardiovascular disease.

Non-HDL cholesterol

Non-HDL cholesterol represents all potentially atherogenic lipoproteins, calculated by subtracting HDL from total cholesterol. It includes LDL, VLDL, and other cholesterol-carrying particles associated with cardiovascular risk.

LDL cholesterol

Known as "bad cholesterol," it can accumulate in arterial walls, forming plaques that narrow blood vessels and increase risk of heart attack and stroke.

HDL cholesterol

Often called "good cholesterol," it helps remove excess cholesterol from your arteries and transports it to the liver for processing, offering protection against atherosclerosis and heart disease.

Cholesterol, total

The overall amount of cholesterol in your bloodstream. High levels can increase risk of heart disease.

Calcium score

A quantitative assessment of calcium-containing plaque in coronary arteries, detected by CT scanning. Serves as an indicator of atherosclerosis progression and cardiovascular risk independent of traditional risk factors.

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